Journal of Urgent Care Medicine

UTI Antibiotic Can Relieve Symptoms In 24 Hours: Study

Gepotidacin, a new oral antibiotic that was approved by the Food and Drug Administration in March 2025 for the treatment of female adults and pediatric patients (≥12 years, ≥40 kg) with uncomplicated urinary tract infections (UTIs) was found to provide rapid symptom improvement—as early as 24 hours after the first dose—according to results of a clinical trial published in JAMA Network Open. The nonrandomized study enrolled 97 patients at 21 U.S. sites who received gepotidacin …

Patients Believe More Antibiotics Are Better

For many common bacterial infections, shorter antibiotic durations are often as effective and safer than longer duration regimens. However, a national survey published in Open Forum Infectious Diseases found that most U.S. adults perceive longer antibiotic courses to be better despite the evidence. Researchers at the University of Utah surveyed 1,475 adults in March–April 2024 about antibiotic use for bacterial respiratory infections. Overall, 60.4% of patients answering the online survey said they preferred courses lasting …

Pediatric Telemedicine Providers Judicious In Prescribing Antibiotics For ARTI

Acute respiratory tract infections (ARTIs) are common diagnoses among pediatric patients, and a recent study of 449,630 pediatric ARTI visits found antibiotics were prescribed less often during telemedicine visits than in-person visits, as published in JAMA Network Open. Antibiotic prescriptions were written during 46.8% (95% confidence interval [CI], 45.1%-48.4%) of primary care in-person visits vs 34.6% (95% CI, 27.0%-42.3%) of primary care telemedicine visits with a difference of −12.1 (95% CI, −19.3 to −5.0) percentage …

Antibiotics Aren’t The Only Drugs That Increase Risk of C. Diff

Researchers found that antibiotics and other commonly prescribed medications substantially increase the risk of Clostridioides difficile infection, and their analysis shows that more drugs impact the gut microbiome than previously believed, as published in Gut. Recent antibiotic exposure (within 30 days) carried the highest risk. Some agents (eg, nitroimidazoles and intestinal anti-infectives) had particularly high odds ratios (OR), likely reflecting treatment-related bias, the authors say. Lipid-lowering agents (aOR 0.8, 95% CI 0.8–0.8) and aspirin (aOR …

Antibiotics Drive ED Visits With Adverse Drug Events Among Kids

Antibiotics are the most commonly implicated drugs in emergency department (ED) visits for adverse drug events (ADEs) among children, as published in the Journal of the Pediatric Infectious Diseases Society. Researchers found antibiotics were implicated in more than one-third of pediatric ADE visits in the United States during 2019-2023, with an estimated average of 47,628 ED visits annually. In some age groups, antibiotics were identified in more than half of the ADE visits. Among the …

Antibiotics In Early Childhood Linked To Chronic Conditions

When kids are exposed to antibiotics before age 2, they may be at greater risk for asthma (hazard ratio [HR] 1.24, 1.22-1.26), food allergy (HR 1.33, 1.26-1.40), and allergic rhinitis (HR 1.06, 1.03-1.10), according to a retrospective analysis published in the Journal of Infectious Diseases. While the study doesn’t prove that early antibiotic exposure caused the conditions, the authors note that antibiotics do play a critical role in combatting bacterial infections. Researchers studied antibiotic exposure …

Recurrent Neuropsychiatric Symptoms in a Patient With Repeated Exposure to Metronidazole: A Case Report

Urgent Message: Metronidazole, even during short courses of therapy, can result in disabling neuropsychiatric symptoms. It is important for clinicians to be knowledgeable about these relatively uncommon but serious adverse medication reactions. Faren Clum, MD; Joshua Russell, MD, MSc, ELS, FCUCM, FACEP Citation: Clum F, Russell J. Recurrent Neuropsychiatric Symptoms in a Patient With Repeated Exposure to Metronidazole: A Case Report. J Urgent Care Med. 2025; 19(7):37-41 Abstract Introduction: Metronidazole is a commonly prescribed antibiotic. …

Which Children Receive First-Line Antibiotics in Urgent Care Most Often?

In a new study of children 6 to 18 months of age, researchers found the odds of receiving first-line antibiotic therapy in pediatric urgent care centers (PUCs) were lower among White children and those with commercial insurance than in other groups. Authors of the study presented in Infection Control & Hospital Epidemiology looked at guideline-recommended first-line antibiotics for acute respiratory infections (ARIs) for 396,340 encounters at 28 PUCs in the United States over 1 year. …

Amoxicillin-Clavulanate Shows Slightly More Risk of Issues Than Amoxicillin

In a study of 320,141 children published in JAMA Network, researchers found those treated with amoxicillin-clavulanate had a slightly higher risk of treatment failure (defined as lack of effectiveness or intolerability) compared with amoxicillin. And for those treated with amoxicillin-clavulanate, there was also a higher risk of gastrointestinal symptoms and yeast infections. Accessing treatment in urgent care was more common among patients who received amoxicillin-clavulanate (9.6%) than those who received amoxicillin (5.9%), and urgent care …

Why Patients Self-Medicate With Leftover Antibiotics

Researchers surveyed adult patients in the waiting rooms of 6 public, safety-net primary care clinics and 2 private emergency departments in Texas and found that more than half of the respondents said they would use leftover antibiotics if they were feeling sick. Among the 546 volunteering patients surveyed, the most common situations that would inspire patients to use non-prescription antibiotics were having access to leftover antibiotics (50.4%), experiencing symptom improvement with prior use of antibiotics …

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