Oral Antihistamines Don’t Help Atopic Dermatitis

Oral Antihistamines Don’t Help Atopic Dermatitis

Routine oral antihistamines provide little benefit for moderate to severe atopic dermatitis, according to a new meta-analysis published in The BMJ. Researchers evaluated 47 trials involving 6,230 children and adults with moderate to severe atopic dermatitis across more than a dozen countries to determine whether adding oral antihistamines improves eczema outcomes. Although second-generation antihistamines (eg, cetirizine, loratadine, fexofenadine) produced statistically significant reductions in eczema severity and itch, the improvements were below established thresholds for clinical …

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Majority of Symptomatic Respiratory Infections Managed At Home

Majority of Symptomatic Respiratory Infections Managed At Home

Respiratory viruses can impact infants more severely than older children, and symptoms run the gamut, according to a new study in Pediatrics. Researchers at Cincinnati Children’s Hospital Medical Center followed 1,223 healthy children from infancy through age 5 from November 2019 to August 2025 and analyzed 15,898 laboratory-confirmed, single-pathogen respiratory infections to characterize symptom patterns and clinical outcomes. Rhinorrhea, cough, malaise, and fatigue were the most common symptoms. The authors also found that compared with …

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Measles Outbreak On Pace To Surpass Last Year’s High Case Counts

Measles Outbreak On Pace To Surpass Last Year’s High Case Counts

In recent days, the Centers for Disease Control and Prevention (CDC) confirmed 2,318 measles cases were reported in the United States for the year so far—outpacing the 2,289 confirmed measles cases for all of 2025. And just like last year, 93% of cases are among people who were unvaccinated or had unknown vaccine status, and 20% of cases are among children under the age of 5 years. So far, 151 measles cases have resulted in …

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New Acetaminophen-Naproxen Drug Combines 2 OTC Pain Relievers

New Acetaminophen-Naproxen Drug Combines 2 OTC Pain Relievers

The Food and Drug Administration (FDA) has approved the combination of acetaminophen 325 mg and naproxen sodium 110 mg tablets as the first fixed-dose, over-the-counter (OTC) product to pair these 2 pain relief ingredients. The label recommends 1 dose every 12 hours for adults and children aged 12 years and older. It is indicated for temporary relief of common complaints such as headache, muscular aches, and back pain. And like other naproxen products, it should …

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POC Test Helps Identify What’s Causing That Sore Throat

POC Test Helps Identify What’s Causing That Sore Throat

Sore throat is among the top complaints presenting to urgent care, and determining the best options for treatment is essential to avoid unnecessary antibiotic prescribing, according to a study recently published in Open Forum Infectious Diseases. In a small sample of 200 urgent care patients with acute pharyngitis or fever—including pediatric and higher-risk adult populations—researchers evaluated a rapid multiplex nucleic acid amplification test that detects 14 bacterial and viral pathogens. At least 1 pathogen was …

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Heat Illnesses Have Cardiovascular Implications

Heat Illnesses Have Cardiovascular Implications

Exertional heat illness is a largely preventable cause of illness and death among physically active people, including athletes and outdoor workers, and the New England Journal of Medicine is promoting a comprehensive review article that was published this spring to remind clinicians of best practices during these sizzling summer months. The review emphasizes that heat illness can occur even in moderate weather when metabolic heat production exceeds the body’s ability to dissipate heat. Clinicians should …

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Deep Dive Into Nonspecific Low Back Pain Offers Diagnostic Approach 

Deep Dive Into Nonspecific Low Back Pain Offers Diagnostic Approach 

Low back pain remains a leading cause of pain and disability worldwide, and 90% of patients presenting for care have nonspecific low back pain rather than a serious spinal disorder, according to a new clinical review published in JAMA. Nonspecific low back pain is defined as pain below the costal margin and above the inferior gluteal folds that does not have clinical features associated with an underlying condition or referred pain, according to the authors. …

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Adults With Health Conditions Have Higher Incidence of Severe RSV

Adults With Health Conditions Have Higher Incidence of Severe RSV

Researchers found adults with underlying high-risk conditions (HRCs)—such as asthma, congenital immunodeficiency, chronic kidney disease, and others—had a higher risk of severe respiratory syncytial virus (RSV) infection than those without such conditions. A community-based study published in Open Forum Infectious Disease followed 7,501 adults aged 18–64 years over 2 RSV seasons. Overall, RSV acute respiratory infection rates were similar in adults with and without HRCs (17.9 cases per 1,000 person-years vs 14.8 cases per 1,000 …

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Annoying Flu Symptoms Can Linger For Weeks

Annoying Flu Symptoms Can Linger For Weeks

Many patients presenting to urgent care with flu symptoms just want relief from the annoyance of their sore throat or body aches. A new study of 724 U.S. adults with confirmed influenza during the 2024–2025 season published in BMC Infectious Diseases found flu symptoms were greatest during the first few days of the illness but often continued on beyond the expected time to recover. In a survey with a selection of 12 flu-related symptoms, participants …

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COVID Antiviral Found Safe For Younger Kids

COVID Antiviral Found Safe For Younger Kids

Researchers found the oral antiviral drug nirmatrelvir/ritonavir (Paxlovid) is safe for kids as young as age 6 with mild/moderate COVID-19 who were at increased risk for severe disease, as published in Pediatrics. Of the in 75 children in the international study, 81% had 1 risk factor for severe COVID-19, most commonly obesity (49%) or chronic lung disease (40%). Additionally, 56% were unvaccinated. Children aged 6–17 years who weighed 40 kg or more received 300 mg …

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