Oral Drug Offers Options For Complicated UTI

Oral Drug Offers Options For Complicated UTI

The Food and Drug Administration (FDA) this month approved tebipenem pivoxil for adults with complicated urinary tract infections (cUTIs), including pyelonephritis, in patients who have limited or no alternative oral treatment options. Marketed as Utebzi, it is one of the more significant antibiotic approvals in recent years because it is the first oral carbapenem antibiotic available in the United States, according to manufacturer GSK. Until now, carbapenems (eg, ertapenem, meropenem, and imipenem) have generally required …

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Encouraging Trends Found in Recent UTI Prescribing Practices

Encouraging Trends Found in Recent UTI Prescribing Practices

Researchers from Boston Children’s Hospital analyzed US emergency department visits for pediatric urinary tract infections (UTIs) to uncover trends in antibiotic prescribing practices. As reported by CIDRAP, from 2011 to 2020, use of trimethoprim-sulfamethoxazole for pediatric UTIs prescriptions declined from 20.6% to 9.9% of visits—which was considered encouraging against concerns for increasing drug resistance—and the use of enteral first-generation cephalosporins increased from 15.2% to 32.6% of visits. Meanwhile, use of enteral third-generation cephalosporins remained flat. …

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A Quality Improvement Project to Improve Management of Urinary Tract Infections in a System of Pediatric Urgent Care Centers

A Quality Improvement Project to Improve Management of Urinary Tract Infections in a System of Pediatric Urgent Care Centers

Urgent message: Urinary tract infection is a common diagnosis in pediatric urgent care. As such, efforts must be made to ensure antibiotics are prescribed only when necessary and to decrease the rate of unnecessary prescribing. Benjamin Klick, MD; Tammy Speerhas, DNP, FNP-C; Jessica Parrott, DNP, CPNP-PC, CNE; Jeffrey Bobrowitz, MD; Anne McEvoy, MD; Debra Conrad, MD, Jade Eves, PA-C; Theresa Guins, MD Citation: Klick B, Speerhas T, Parrott J, Bobrowitz J, McEvoy A, Conrad D, …

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Evaluation, Identification, and Treatment of Urinary Tract Infections

Evaluation, Identification, and Treatment of Urinary Tract Infections

Urgent message: Urinary tract infections are a common cause of abdominal pain and a common presenting complaint in urgent care. Proper diagnosis, treatment, and patient education on preventive measures are key to optimal outcomes. William Gluckman, DO, MBA, FACEP, Karen Keaney Gluckman, MSN, APN, C, CWCN, CCCN The global term urinary tract infection (UTI) incorporates cystitis and infection involving the bladder (a lower tract source), as well as pyelonephritis, an infection involving the kidneys (an …

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