Journal of Urgent Care Medicine

CGRP Drugs Help Most For Migraine

A systematic review of 43 randomized trials involving more than 14,000 patients found that evidence shows several newer calcitonin gene–related peptide (CGRP)-targeted drugs can reduce chronic migraine frequency by about 2 headache days per month compared with placebo. In the review published in the Annals of Internal Medicine, researchers also found the CGRPs may achieve at least a 50% reduction in migraine frequency, although those findings were sourced from a limited number of studies. Botulinum …

Abstracts in Urgent Care – May 2026

Variation in Pretibial Laceration Management Take Home Point: Assessment and management of pretibial lacerations lack consistent standardized guidelines, which is needed to improve patient outcomes. Citation: Shafi S, Shaw A, Koubeh W, et al. Management of pretibial lacerations: A systematic review. Injury. 2026;57(4):113101. doi: 10.1016/j.injury.2026.113101 Relevance: Pretibial lacerations are commonly encountered in both emergency departments (EDs) and urgent care (UC) settings, especially among older adults. Despite their frequency, management approaches vary widely across settings and …

Blocking the Pain: Nerve Block in the Treatment of Headache in Urgent Care

Urgent Message: Although greater occipital nerve block has demonstrated positive effectiveness and few risks as a treatment for acute headache, it is not commonly used. With more familiarity, urgent care clinicians may consider it a useful treatment modality. Elizabeth Reynolds, PA-C, MS Key Words: Migraine, Headaches, Nerve Block Abstract Headaches are a common presentation in urgent care clinics. Various medication options are available but can sometimes be limited for use due to allergies, side effects, …

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