Journal of Urgent Care Medicine

AOM Treatment Shows No ‘Weekend Effect’

In a retrospective study from the pediatric emergency department (PED) at Samson Assuta Ashdod University Hospital in Israel, researchers evaluated whether children with uncomplicated acute otitis media (AOM) received different care on weekends vs weekdays (the “weekend effect”), knowing that community-based pediatric clinics are closed on weekends. The review, published in the Pediatric Infectious Disease Journal, included 288 children aged 6 months to 10 years who presented to the PED between 2017 and 2024. Overall, …

Amoxicillin Has Slight Advantage Over Amoxicillin-Clavulanate For Acute Sinusitis

In a large observational study of 521,244 adults with acute sinusitis published in JAMA, researchers found outcomes were similar between patients treated with standard-dose amoxicillin-clavulanate and those treated with standard-dose amoxicillin. The study compared outpatient outcomes from 2018 through 2023 for new users of amoxicillin-clavulanate (875–125 mg, 2 times daily) or amoxicillin (875 mg twice daily or 500 mg, 3 times daily). Treatment failure was low overall (3.1%) and did not differ between groups. Only …

Amoxicillin-Clavulanate Shows Slightly More Risk of Issues Than Amoxicillin

In a study of 320,141 children published in JAMA Network, researchers found those treated with amoxicillin-clavulanate had a slightly higher risk of treatment failure (defined as lack of effectiveness or intolerability) compared with amoxicillin. And for those treated with amoxicillin-clavulanate, there was also a higher risk of gastrointestinal symptoms and yeast infections. Accessing treatment in urgent care was more common among patients who received amoxicillin-clavulanate (9.6%) than those who received amoxicillin (5.9%), and urgent care …

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