Clinical

Some corners of the public seem to have fallen back into the notion that, while patients with comorbid conditions are at higher risk, a case of COVID-19 is not that different from a bad case of influenza—you feel bad for a week or two and then you’re back on your feet. New data published in the Annals of Internal Medicine should help you disavow them of that misconception, however. An article there indicates that up …

The United States is already grappling with a deadly resurgence of the COVID-19 virus, but news from the United Kingdom indicates we could see a dire situation turn even worse if we’re not careful. The government there, perhaps wary of repeating mistakes that allowed the virus to run rampant last spring, has already implemented a partial shutdown of nonessential businesses and services in order to discourage widespread contact among the public. This is not “just” …

A pair of new COVID-19 self-test kits received approval from the Food and Drug Administration this week. The biggest—and possibly most concerning—difference between the two is that one is available without a prescription. The first, BinaxNOW from Abbott, was already approved for, and being administered by, healthcare professionals. Now, however, patients who want to be tested can log on to an Abbott app with their smartphone to be connected to a healthcare provider at eMed. …

Media coverage of two British healthcare workers who experienced anaphylaxis after receiving the Pfizer/BioNT version of the COVID-19 vaccine last week led to widespread presumption that the vaccine should not be given to patients with a history of allergic reactions to vaccinations. In an effort to dispel that notion, the Centers for Disease Control and Prevention issued an announcement stating that the vaccine is believed to be safe for use in all patients, but that …

Obesity, hypertension, lung ailments, and any number of conditions have been linked to increased risk for complications in patients with COVID-19. While chronic kidney disease has not often gotten much attention, a new study published by PLOS ON indicates that CKD could actually be the leading risk factor for hospitalization in infected patients. The paper reflects analysis of the electronic health records of 12,971 individuals, 1,604 of whom had CKD; of those, 354 (22%) required …

Readers of JUCM News know the Centers for Disease Control and Prevention shortened the amount of time it recommends quarantining for certain people with, or who have been exposed to, COVID-19. Now the College of Urgent Care Medicine is advising urgent care providers to read the proverbial fine print in that guidance. The CUCM stresses that the CDC statement offers “acceptable alternatives” to the quarantine periods, in spite of the fact that multiple media reports …

The first evidence that rates of venous and arterial thromboembolism are high in patients with COVID-19 has arrived, in the form of an article just published in The Lancet’s online journal EClinicalMedicine. The meta-analysis of 42 studies involving 8,271 patients notes that rates range anywhere from 20% to 70% among patients who have been diagnosed with the virus. Overall mortality rate among patients with COVID-19 and thromboembolism was 23%, vs 13% without thromboembolism. The authors concluded …

Just last week we told you about an Emergency Use Authorization from the Food and Drug Administration for a home COVID-19 test—along with an admonition that self-testing may make already-insufficient reporting of COVID-19 data even worse. As the pandemic continues and we wade deeper into flu season, the FDA has now authorized the first home dual test for COVID-19 and influenza A and B. Available by prescription only, the Quest Diagnostics product includes a self-collection …

Anecdotal evidence that ongoing direct oral anticoagulant (DOAC) use might reduce a patient’s risk for severe disease with COVID-19 appears to have been wishful thinking, if the results of a study just published in the Journal of Internal Medicine are any indication. The authors found no association between DOAC use and lower incidence of hospital admission for COVID-19, or a composite of intensive care unit admission of death. As such, they concluded that DOAC use …

As many as 40 million doses of coronavirus vaccine may be available in the United States by the end of this year. While that’s clearly good news, it’s significantly fewer than will be needed to offer widespread protection and make a dent in the pandemic. That being the case, the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices has issued its official recommendations on who should be able to be immunized first …