Severe Flu Season Also Associated With Cases of Rare Pediatric Encephalopathy

Severe Flu Season Also Associated With Cases of Rare Pediatric Encephalopathy

The last influenza season (2024–2025) was categorized as high-severity with more cases and hospitalizations than the previous 14 years. New data from the Centers for Disease Control and Prevention (CDC) is also showing 109 rare cases of pediatric influenza-associated encephalopathy (IAE) occurred last year as well. Overall, 74% of IAE patients were admitted to an intensive care unit, and 19% died. Only 16% of vaccine-eligible IAE patients had received the 2024–2025 flu vaccine. Of the …

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Study Observes Changes in EDs After PE Acquisition 

Study Observes Changes in EDs After PE Acquisition 

Whether private equity (PE) is friend or foe in the healthcare market is still a subject of intense debate. A new study of emergency department (ED) visits published in the Annals of Emergency Medicine found that patient mortality and outside transfers increased in PE-owned hospitals once the hospital was acquired. These EDs experienced 7 additional deaths per 10,000 visits after acquisition relative to control (13.4% increase from a raw baseline of 52.4 deaths per 10,000; …

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New Gastroparesis Guidelines Focus on First-Line Treatments

New Gastroparesis Guidelines Focus on First-Line Treatments

A new clinical practice guideline from the American Gastroenterological Association helps support physicians who are treating patients with gastroparesis. The condition is difficult to diagnose and treat, so the new guidelines outline the current state of the evidence for clinical options, as published in Gastroenterology. Part of the motivation for publishing the insight comes from possible new risks for gastroparesis related to glucagon-like peptide-1 (GLP-1) receptor agonists that are increasingly being used by patients for …

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Kids’ Hypertension Can Lead to Adult Cardiovascular Disease and Death

Kids’ Hypertension Can Lead to Adult Cardiovascular Disease and Death

Children with elevated blood pressure in childhood can experience a greater risk of early death from cardiovascular disease (CVD) in adulthood, a new long-term study in JAMA finds. At baseline, 21% of the 37,081 children studied were classified as having hypertension, while about 19% were classified as having elevated blood pressure. Participants (born from 1959 to 1966) were followed to a median age of 54 years. At follow-up, a 1-SD higher systolic blood pressure measure …

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No Causal Link to Autism or ADHD Found In Prenatal Opioid Exposure

No Causal Link to Autism or ADHD Found In Prenatal Opioid Exposure

A large Swedish study that examined prenatal exposure to prescribed opioid pain medications and the child’s risk of later developing autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) found no causal link between prescribed opioid use during pregnancy and risk of the conditions. As published in PLOS Medicine, researchers analyzed data from more than 1.2 million children for ASD (2007–2018) and more than 900,000 children for ADHD (2007–2015). By the time the subjects were 10 …

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Younger School Kids More Likely To Test Positive For Respiratory Viruses

Younger School Kids More Likely To Test Positive For Respiratory Viruses

A study in a public school system found that younger students had the highest rates of respiratory virus detections compared to older grades, as published in Pediatrics. From November 2022 to May 2023, 816 students and staff in the North Kansas City, Missouri, school system provided 5,981 nasal swab samples and 5,198 monthly symptom surveys for the pre-kindergarten (pre-K) through 12th grade classes for 24.5 weeks. Overall, 85.5% of students and staff had at least …

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Parents Want Diagnostics For Kids’ Diarrhea, Despite Clinician Skepticism

Parents Want Diagnostics For Kids’ Diarrhea, Despite Clinician Skepticism

Parents and clinicians don’t always share the same perspectives on diagnostic testing for pediatric diarrhea, according to a qualitative study published in JAMA Network Open. Interviews with 44 parents (91% female; median age, 34 years) and 16 clinicians (69% female; median age, 42 years) from 5 urgent care sites and 1 emergency department in Utah demonstrated the differences in their expectations. Participating clinicians included 10 physicians (62%) and 6 nurse practitioners or physician assistants (38%). …

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Campaign Increases Urgent Care Adherence to 5-Day Antibiotic Prescribing

Campaign Increases Urgent Care Adherence to 5-Day Antibiotic Prescribing

In a quasi-experimental study involving 2 Denver Health urgent care centers, an antibiotic stewardship program known as the Take 5 Campaign increased the rates of adherence to a recommended 5-day antibiotic prescribing duration, according to a new study published in Open Forum Infectious Diseases.  “Antibiotic stewardship in urgent care is critical,” says Lindsey E. Fish, MD, study author and Editor in Chief of JUCM. “While many programs focus on decreasing inappropriate antibiotic prescribing, ensuring the …

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OTC Allergy Nasal Spray Could Protect Against COVID Infection: Phase 2 Study

OTC Allergy Nasal Spray Could Protect Against COVID Infection: Phase 2 Study

A phase 2 clinical trial found that azelastine nasal spray could potentially prevent COVID-19 infections in healthy adults, as published in JAMA Internal Medicine. Among 450 study participants, SARS-CoV-2 infection as determined by polymerase chain reaction testing occurred in 2.2% of those using azelastine compared with 6.7% in the placebo group, representing a 67% relative risk reduction (odds ratio, 0.31; 95% confidence interval, 0.11-0.87). Symptomatic COVID-19 infections were also less frequent with azelastine (1.8% vs …

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FDA Warns More Kids Are Getting Sick From Exposure To Nicotine Pouches

FDA Warns More Kids Are Getting Sick From Exposure To Nicotine Pouches

The Food and Drug Administration (FDA) is warning clinicians and parents about the potential health risks of nicotine pouches, especially those that do not have child-resistant packaging. Reports of accidental exposures to nicotine pouches have increased with some cases leading to nicotine poisoning, and according to FDA, children can experience toxic effects after exposure to as little as 1-4 milligrams of nicotine. Symptoms can include confusion, vomiting, and loss of consciousness. In a statement, the …

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