Nirsevimab May Help Reduce Antibiotic Prescribing for Newborns and Infants 

Nirsevimab May Help Reduce Antibiotic Prescribing for Newborns and Infants 

Researchers examining electronic health record data found nirsevimab administration was associated with reduced antibiotic prescribing among infants during their first respiratory syncytial virus (RSV) season, as published in Clinical Infectious Diseases. Among 15,341 eligible infants from 32 pediatric practices in the study, 7,413 (48.3%) received nirsevimab. At 6 months, nirsevimab was associated with a 14.4% reduction in antibiotic prescribing for outpatient acute respiratory tract infections and a 40.3% reduction for outpatient bronchiolitis. Antibiotic prescribing associated …

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Pathogen Findings Don’t Always Signal UTIs

Pathogen Findings Don’t Always Signal UTIs

Researchers found that women with urinary tract infection (UTI), those with noninfectious lower urinary tract symptoms (LUTS), and control subjects exhibited similar uropathogen levels when evaluated with quantitative polymerase chain reaction (qPCR) testing, as published in Clinical Infectious Diseases. They analyzed urine from 502 women: 104 with recurrent UTI and acute symptoms; 354 with noninfectious LUTS; and 44 asymptomatic controls. The qPCR tests detected bacterial DNA in nearly all participants, including E coli in 97.3%, …

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Urgent Care Encounters Provide Clues For Flu Vaccine Effectiveness

Urgent Care Encounters Provide Clues For Flu Vaccine Effectiveness

The 2024–2025 influenza season was characterized as having high severity, and in research published in Open Forum Infectious Diseases, researchers found flu shots provided protection not just against hospitalization but also against emergency department (ED) and urgent care (UC) visits during that time. They evaluated influenza vaccine effectiveness using data from 7 healthcare systems in 8 states across 102,854 ED/urgent care visits among children and 233,411 visits among adults. Overall, vaccination was 54% effective against …

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Flu Shots Hold Their Own For The Upcoming Season

Flu Shots Hold Their Own For The Upcoming Season

Medical societies are doubling down on recommendations for flu vaccines for the upcoming 2026–2027 season, which starts around the beginning of October. The American Academy of Pediatrics (AAP), for example, is reinforcing its recommendations for flu vaccines for all children ages 6 months and older without contraindications, as published this week in Pediatrics. AAP specifically notes in a separate press release that the vaccines have been thoroughly studied and are safe for children. For the …

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Rise In Vibrio Vulnificus Deaths Prompts Public Health Warnings

Rise In Vibrio Vulnificus Deaths Prompts Public Health Warnings

State health departments are reporting an increase in severe Vibrio vulnificus infections along the Gulf Coast in recent weeks with the highest concern currently centered around Louisiana, which has recorded 9 confirmed cases for the year so far. All 9 patients were hospitalized, and 5 have died. Louisiana normally averages about 7 cases and 1 death per year, so the case counts and deaths have prompted public warnings for consumers to stay out of the …

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Bacterial Vaginosis Linked to Higher Rates of STI Coinfections

Bacterial Vaginosis Linked to Higher Rates of STI Coinfections

Among patients presenting for vaginitis evaluation, bacterial vaginosis was found to be strongly associated with increased risk of nonviral sexually transmitted coinfection, as published in O&G Open. Researchers retrospectively studied 1.5 million women who received molecular testing for bacterial vaginosis, vulvovaginal candidiasis, and sexually transmitted infection (STI) from 2022–2024 in the United States. They found bacterial vaginosis was detected in 38.7% of patients and vulvovaginal candidiasis was detected in 28.5% of patients—with 10.8% of patients …

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Cannabis Hyperemesis Syndrome Records Triple With New ICD-10 Code

Cannabis Hyperemesis Syndrome Records Triple With New ICD-10 Code

A new Centers for Disease Control and Prevention analysis identified 199,565 emergency department (ED) visits involving cannabis hyperemesis syndrome (CHS) in the United States from January 2023 through May 2026 and found that new coding helped to document patient cases of CHS. Researchers evaluated the time period before and after October 1, 2025, when the dedicated ICD-10-CM diagnosis code for CHS (R11.16) went into effect. The introduction of the ICD-10 code provided a direct way …

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Oral Antihistamines Don’t Help Atopic Dermatitis

Oral Antihistamines Don’t Help Atopic Dermatitis

Routine oral antihistamines provide little benefit for moderate to severe atopic dermatitis, according to a new meta-analysis published in The BMJ. Researchers evaluated 47 trials involving 6,230 children and adults with moderate to severe atopic dermatitis across more than a dozen countries to determine whether adding oral antihistamines improves eczema outcomes. Although second-generation antihistamines (eg, cetirizine, loratadine, fexofenadine) produced statistically significant reductions in eczema severity and itch, the improvements were below established thresholds for clinical …

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Majority of Symptomatic Respiratory Infections Managed At Home

Majority of Symptomatic Respiratory Infections Managed At Home

Respiratory viruses can impact infants more severely than older children, and symptoms run the gamut, according to a new study in Pediatrics. Researchers at Cincinnati Children’s Hospital Medical Center followed 1,223 healthy children from infancy through age 5 from November 2019 to August 2025 and analyzed 15,898 laboratory-confirmed, single-pathogen respiratory infections to characterize symptom patterns and clinical outcomes. Rhinorrhea, cough, malaise, and fatigue were the most common symptoms. The authors also found that compared with …

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Measles Outbreak On Pace To Surpass Last Year’s High Case Counts

Measles Outbreak On Pace To Surpass Last Year’s High Case Counts

In recent days, the Centers for Disease Control and Prevention (CDC) confirmed 2,318 measles cases were reported in the United States for the year so far—outpacing the 2,289 confirmed measles cases for all of 2025. And just like last year, 93% of cases are among people who were unvaccinated or had unknown vaccine status, and 20% of cases are among children under the age of 5 years. So far, 151 measles cases have resulted in …

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