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In 2023, the American Heart Association (AHA) introduced a staging construct for cardiovascular, kidney, and metabolic (CKM) syndrome. Subsequently, a 2024 JAMA article found among a study population of 10,762 U.S. adults, almost 90% met criteria for CKM syndrome (stage 1 or higher), and 15% met criteria for advanced stages between 2011 and 2020. In a new survey of 4,000 adults, AHA found that only 12% of respondents had heard of CKM, and 68% incorrectly believe it’s best to manage their overlapping CKM health conditions individually, even though the diseases are pathophysiologically interrelated. Risk factors for CKM syndrome include high blood pressure, abnormal cholesterol, high blood glucose, excess weight, and reduced kidney function, which often can be improved with lifestyle changes, according to AHA.
Now what? AHA is set to issue inaugural guidelines on CKM syndrome in early 2026. In the meantime, health organizations can participate in scientific implementation efforts, found on the AHA website.