Study Finds New Semaglutide Benefits, No Link to Suicidal Thoughts

Study Finds New Semaglutide Benefits, No Link to Suicidal Thoughts

A study published in the Lancet last week investigated millions of U.S. medical records to determine whether semaglutide increased the risk of neurological and psychiatric conditions within the first year of use compared to 3 other common antidiabetic medications. Authors found no association between semaglutide and a higher risk of the 22 studied conditions (eg, psychosis; bipolar disorder; depression; anxiety; opioid and alcohol use disorder; etc.). In fact, patients on semaglutide showed lower rates of …

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Studies Find No Increased Risk of Suicide With Semaglutide

Studies Find No Increased Risk of Suicide With Semaglutide

The glucagon-like peptide 1 (GLP-1) receptor agonist semaglutide (Wegovy, Ozempic) was found to demonstrate no increased risk of suicidal ideation in patients with obesity or type 2 diabetes, according to retrospective analyses of electronic health records examining these patient populations, published in Nature Medicine. Researchers’ analysis of 240,618 patients who were overweight/obese showed that those taking semaglutide had a significantly lower risk (0.11%) of suicidal ideation compared with those using non-GLP-1 anti-obesity medications (0.43%). In …

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Patients More Likely to Stick With Semaglutide Treatment

Patients More Likely to Stick With Semaglutide Treatment

Patients taking the GLP-1 weight loss drug semaglutide were 3 times more likely to maintain adherence to their medication regimens a year later when compared to other drug options, according to a Cleveland Clinic study. As described in Obesity, researchers examined health records of 1,911 adults in two states and found 40% of semaglutide patients were still filling their prescriptions 12 months after the initiation of treatment. Patients using other anti-obesity drugs, such as orlistat, liraglutide, …

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