Studies Find No Increased Risk of Suicide With Semaglutide

Studies Find No Increased Risk of Suicide With Semaglutide

The glucagon-like peptide 1 (GLP-1) receptor agonist semaglutide (Wegovy, Ozempic) was found to demonstrate no increased risk of suicidal ideation in patients with obesity or type 2 diabetes, according to retrospective analyses of electronic health records examining these patient populations, published in Nature Medicine. Researchers’ analysis of 240,618 patients who were overweight/obese showed that those taking semaglutide had a significantly lower risk (0.11%) of suicidal ideation compared with those using non-GLP-1 anti-obesity medications (0.43%). In …

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Patients More Likely to Stick With Semaglutide Treatment

Patients More Likely to Stick With Semaglutide Treatment

Patients taking the GLP-1 weight loss drug semaglutide were 3 times more likely to maintain adherence to their medication regimens a year later when compared to other drug options, according to a Cleveland Clinic study. As described in Obesity, researchers examined health records of 1,911 adults in two states and found 40% of semaglutide patients were still filling their prescriptions 12 months after the initiation of treatment. Patients using other anti-obesity drugs, such as orlistat, liraglutide, …

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