Labels May Skew Statin Drug’s True Side Effects 

Labels May Skew Statin Drug’s True Side Effects 

Many of the adverse events listed on the labels for statin drugs may not be supported by good evidence of a causal relationship, according to an analysis in The Lancet. Adverse events examined from 19 double-blind trials do not seem to show statin therapy causes cognitive impairment, depression, sleep disturbance, and peripheral neuropathy. Four events did have significance in the study. The authors say their analysis “has confirmed that statin therapy increases hepatic transaminase and …

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Younger Adults With High Cholesterol Lag In Statin Treatment

Younger Adults With High Cholesterol Lag In Statin Treatment

A large study of 771,681 adults aged 18–39 found that young people with high LDL cholesterol rarely begin statin therapy, despite guideline recommendations, as published in the Journal of the American College of Cardiology and presented at the American Heart Association’s 2025 Scientific Sessions. Among young adult members of Kaiser Permanente Southern California with LDL-C of 190 mg/dL or higher, just 28.4% started a statin drug within 1 year, and less than half (45.7%) had …

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