Journal of Urgent Care Medicine

DoxyPEP May Reduce Use of Antibiotics For STIs

A study published in the Journal of Antimicrobial Chemotherapy analyzed data from men who have sex with men who were either living with HIV or using HIV pre-exposure prophylaxis. The researchers found that using doxycycline post-exposure prophylaxis (doxyPEP) after unprotected sex significantly reduced the need for antibiotics to treat bacterial sexually transmitted infections (STIs). Between August 2022 and July 2024, 754 men in Italy were prescribed doxyPEP, and 222 (29.4%) reported using it during follow-up. …

Doxy PEP Demonstrates Real-World Effectiveness

A study of 2,083 patients found that doxycycline postexposure prophylaxis (doxy PEP) was highly effective in preventing sexually transmitted infections (STIs) in a real-world setting. Conducted from April 2019 to July 2024 at the Los Angeles LGBT Center, the study analyzed patient demographics, STI testing history, and doxy PEP use patterns. Nearly half of participants were aged 31–40, over half were White, and most (85.2%) were gay or bisexual men. Most were not diagnosed with …

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