Journal of Urgent Care Medicine

OTC Allergy Nasal Spray Could Protect Against COVID Infection: Phase 2 Study

A phase 2 clinical trial found that azelastine nasal spray could potentially prevent COVID-19 infections in healthy adults, as published in JAMA Internal Medicine. Among 450 study participants, SARS-CoV-2 infection as determined by polymerase chain reaction testing occurred in 2.2% of those using azelastine compared with 6.7% in the placebo group, representing a 67% relative risk reduction (odds ratio, 0.31; 95% confidence interval, 0.11-0.87). Symptomatic COVID-19 infections were also less frequent with azelastine (1.8% vs …

Active People Had Lower Odds of COVID-19 Infection

A study in JAMA Network Open found people who engaged in higher levels of physical activity before the pandemic experienced lower odds of developing COVID-19 and related hospitalizations from May 2020 through May 2022. In studying patients 45 years or older with 5,890 cases of COVID-19 and 626 hospitalizations, researchers found those who achieved at least 7.5 hours per week of physical activity pre pandemic had significantly reduced odds of COVID-19 diagnosis and hospitalization compared …

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