Recommendations Say More Patients Should Start Antihypertensive Medication

Recommendations Say More Patients Should Start Antihypertensive Medication

Recent updates to blood pressure (BP) guidelines published in the Journal of the American College of Cardiology have lowered the threshold for initiating hypertension treatment among low-risk patients. According to the 2025 joint guideline from the American Heart Association and the American College of Cardiology, adults without clinical cardiovascular disease (CVD) and with an estimated 10-year CVD risk below 7.5% should begin antihypertensive therapy if their average systolic BP remains at 130 mm Hg or …

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Bedtime Antihypertensive Regimens Offer No Special Benefit

Bedtime Antihypertensive Regimens Offer No Special Benefit

A Canadian trial published in JAMA  involving 3,200 primary care patients (56.4% female; median age, 67 years) evaluated the timing of antihypertensive medication administration and found no difference in morning vs bedtime dosing. Over a median follow-up of 4.6 years, bedtime dosing was found to be safe but offered no additional cardiovascular benefit. Rates of major cardiovascular events or death were similar between groups (2.3 vs 2.4 per 100 patient-years; adjusted hazard ratio 0.96, 95% …

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