Journal of Urgent Care Medicine

It’s Hard To Predict Who Might Be At Risk For Food Allergies

An analysis of 190 studies including 2.8 million children published in JAMA Pediatrics found that approximately 4.7% of children develop food allergy by age 6. The strongest risk factors for food allergy include several prior allergic conditions: atopic dermatitis in the first year of life (odds ratio [OR] 3.88, risk difference [RD] 12%); allergic rhinitis (OR 3.39, RD 10%); and wheeze (OR 2.11, RD 5%). Markers of skin barrier dysfunction, including elevated transepidermal water loss, …

Oral Drug Targets Chronic Hives

The Food and Drug Administration (FDA) has approved oral remibrutinib, a new drug product, as a second-line treatment for chronic spontaneous urticaria (CSU). Remibrutinib has a unique mechanism to block the activity of Bruton’s tyrosine kinase (BTK), stopping a key pathway of the immune response in CSU, according to a manufacturer press release. The condition is thought to be caused by immune dysregulation, and it is believed that once activated, BTK leads to the release …

New Epinephrine Nasal Spray Aims to Improve User Experience

A new epinephrine nasal spray has been approved by the Food and Drug Administration (FDA) for the treatment of allergic reactions, including anaphylaxis, in adult and pediatric patients who weight at least 66 pounds, according to an FDA press release. Until now, epinephrine has only been available for patients as an injection or auto-injection device. The agency says the new delivery mechanism addresses an unmet need in that some people who need urgent epinephrine treatment …

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