Poliovirus Showing Up in Wastewater in 5 European Countries

Poliovirus Showing Up in Wastewater in 5 European Countries

Countries around the world are reporting wastewater detections of poliovirus. The United Kingdom recently reported 3 wastewater detections of poliovirus type 2, while Germany reported 6 wastewater detections in 6 different cities. Other detections in Finland, Spain, and Poland have been reported recently as well. In general, the European countries that have reported virus detections since September have strong disease surveillance and high routine immunization levels. Meanwhile, Pakistan has reported 3 wild poliovirus type 1 …

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Could the Obesity Trend Be Diminishing? 

Could the Obesity Trend Be Diminishing? 

In 2023, the United States saw a slight decrease in obesity prevalence among adults, according to a new research letter describing body mass index (BMI) data from 2013 to 2023 in JAMA Health Forum. In spite of conflicting trends forecasting increasing obesity rates (ie, BMI equal to or greater than 30) over the next decade, researchers found the mean population BMI rose annually from 2013 to 2021, then plateaued in 2022 at 46%, followed by …

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New HPV Strategy Includes Self-Collection Screening Tests 

New HPV Strategy Includes Self-Collection Screening Tests 

A new draft recommendation from the US Preventive Services Task Force (USPSTF) suggests that testing for human papilloma viruses (HPV) every 5 years starting at age 30 is a preferred screening strategy, emphasizing the need for testing for high-risk HPV with vaginal samples as opposed to the traditional cervical cytology pap tests. The USPSTF notes that the HPV test is more effective than a pap test as a cervical cancer screening tool for ages 30 …

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AI Tool Correctly Detects Epileptic Syndrome in Infants By Watching Videos

AI Tool Correctly Detects Epileptic Syndrome in Infants By Watching Videos

An artificial intelligence (AI) model accurately detected infantile epileptic spasm syndrome through the assessment of smartphone videos captured by families, according to a study published in a medRxiv preprint that has not been peer reviewed. Among the results, the AI model had 82% sensitivity and 90% specificity. The infantile epileptic spasm syndrome diagnosis is considered a neurologic emergency, according to MedPage Today, and experts believe the AI platform has potential as a screening tool. Infants …

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Head-to-Head Study Compares GLP-1 Weight Loss

Head-to-Head Study Compares GLP-1 Weight Loss

In a pharmaceutical head-to-head, tirzepatide was found to provide 47% greater relative weight loss compared to semaglutide. On average, patients using tirzepatide lost 50.3 lbs (22.8 kg), and those using semaglutide lost 33.1 lbs (15.0 kg) after 72 weeks. In addition, for the study’s secondary endpoint, 31.6% of people taking tirzepatide achieved at least 25% body weight loss compared to 16.1% of those taking semaglutide. The randomized, open-label trial included 751 participants across the United …

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Which Children Receive First-Line Antibiotics in Urgent Care Most Often? 

Which Children Receive First-Line Antibiotics in Urgent Care Most Often? 

In a new study of children 6 to 18 months of age, researchers found the odds of receiving first-line antibiotic therapy in pediatric urgent care centers (PUCs) were lower among White children and those with commercial insurance than in other groups. Authors of the study presented in Infection Control & Hospital Epidemiology looked at guideline-recommended first-line antibiotics for acute respiratory infections (ARIs) for 396,340 encounters at 28 PUCs in the United States over 1 year. …

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FDA Keeping Tabs on Montelukast Suicide Risk

FDA Keeping Tabs on Montelukast Suicide Risk

The Food and Drug Administration (FDA) presented the preliminary results of new research on montelukast at the American College of Toxicology meeting recently, describing potential side-effect risks for the oral asthma drug. Montelukast may be leading to mental health conditions and suicide by attaching to multiple brain receptors that are involved in psychiatric functioning, researchers say. According to Reuters, thousands of patients have reported neuropsychiatric episodes, prompting the FDA to launch a comprehensive investigation and …

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AAP Offers Guidelines for Pediatric Opioid Prescribing

AAP Offers Guidelines for Pediatric Opioid Prescribing

The American Academy of Pediatrics (AAP) has issued its first clinical practice guideline on prescribing opioids for outpatient acute pain management in children, published in Pediatrics. The guideline recommends using immediate-release opioids at the lowest dose for age- and weight-appropriateness, with an initial supply of no more than 5 days unless the pain is due to trauma or surgery requiring longer treatment. Codeine and tramadol should not be prescribed to children under 12, adolescents with …

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Amoxicillin-Clavulanate Shows Slightly More Risk of Issues Than Amoxicillin

Amoxicillin-Clavulanate Shows Slightly More Risk of Issues Than Amoxicillin

In a study of 320,141 children published in JAMA Network, researchers found those treated with amoxicillin-clavulanate had a slightly higher risk of treatment failure (defined as lack of effectiveness or intolerability) compared with amoxicillin. And for those treated with amoxicillin-clavulanate, there was also a higher risk of gastrointestinal symptoms and yeast infections. Accessing treatment in urgent care was more common among patients who received amoxicillin-clavulanate (9.6%) than those who received amoxicillin (5.9%), and urgent care …

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About 5% of Adults With RSV Experience Hospitalizations

About 5% of Adults With RSV Experience Hospitalizations

Researchers quantified the real-world risk for hospitalization among adults diagnosed with respiratory syncytial virus (RSV) in outpatient settings in a study presented in JAMA Network Open. They examined all-cause 28-day hospitalization following outpatient RSV infections among all adults as well as a high-risk subgroup of adults across 6 RSV seasons comprising 67,239 outpatient infections. Data revealed approximately 5% of adults experienced all-cause hospitalization within 28 days following outpatient RSV infections. The analysis showed an absolute …

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