Clinical
Evaluation and Management of
Lower Extremity Edema
Urgent message: The high specificity but broad range of possible
causes associated with a primary complaint of lower extremity edema
poses a particular challenge to the urgent care clinician. Proper assess-
ment of the differential diagnoses is the first step toward optimal
outcomes, whether they be facilitated by treatment or referral.
Michael S. Miller, DO
P Introduction
The word circulation is often misused by physicians or
w w w. j u c m . c o m
misunderstood by patients.
While it is usually used in
reference to the peripheral
blood flow in the arteries, cir-
culation more properly refers
to the entire course of blood
flow from the heart through
the peripheral arteries of the
distal tissues via the capillar-
ies, all the way to its return
via the venous system to the
heart. Patients may find it easier
to grasp the true meaning if
you explain that the word it-
self was derived from the
Latin word circulare—to
make a circle.
Equally problematic is the
diagnosis of “poor circula-
tion” made by a simple visual inspection of the legs when,
in fact, no arterial compromise exists. Consideration
should always include both the arterial and the venous.
Arterial circulation can easily be assessed via a well-
taken history (“How far can you walk? Does the pain
make you stop walking? Do you have to rest—and for
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atients presenting to ur-
gent care with a primary
complaint of edema of
the lower extremities of
any duration can pose a
particularly vexing challenge
for the practitioner. While
the symptom is quite spe-
cific, it could be indicative
of any number of diagnoses;
is the root cause chronic ve-
nous insufficiency, or a more
emergent condition requir-
ing immediate referral (e.g.,
deep vein thrombosis)?
Further, how do you dif-
ferentiate between stasis der-
matitis and cellulitis, thereby
avoiding inappropriate an-
tibiotic therapy?
Such determinations are essential preparation for
choosing appropriate treatment or referring the patient
to the appropriate setting for care.
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