Case Report
Supraventricular Tachycardia in
a Child with Williams Syndrome
after Nebulized Albuterol
Urgent message: Clinicians must be prepared for the possibility of
supraventricular tachycardia after administration of nebulized albuterol
in patients of any age, especially in the presence of heart disease.
Muhammad Waseem, MD, Padma Gadde, MD, and Gerard Devas, MD
Introduction sthma is the most common lung disease in children.
Five percent of children in the United States have
asthma, and status asthmaticus—the leading cause
of admission due to asthma exacerbation—accounts
for approximately 10% of visits to pediatric emer-
gency departments. 1
Here, we present a case involving a 2-year-old asth-
matic boy with Williams syndrome (WS) who developed
supraventricular tachycardia (SVT) following standard
administration of albuterol.
This case report emphasizes the need for increased
awareness among urgent care and emergency physi-
cians, and describes the use of adenosine in the treat-
ment of SVT due to  2 agonist albuterol.
A In the emergency department, he was in moderate res-
piratory distress with a temperature of 102.3 ° F, respirato-
ry rate of 34 breaths per minute, heart rate of 169 beats
per minute, and oxygen saturation of 95%. He had
coarse breath sounds with wheezing.
Cardiac examination revealed a regular rate and
rhythm and no murmur. The boy was brought to an
asthma room because of his respiratory distress and
wheezing and started on nebulized albuterol. A chest
radiograph revealed right upper lobe pneumonia. The
heart size and pulmonary vascularity were normal. The
patient was placed on a pulse oximeter.
The following were noted:
Ⅲ Three episodes of vomiting during second nebuliz-
er treatment
Ⅲ Heart rate of 242 beats per minute
Case A 2-year-old boy with WS presented to the emergency
department with a three-day history of fever, cough, and
wheezing. He received three doses of nebulized albuterol
and was diagnosed with reactive airway disease and
bilateral otitis media. He was discharged on oral amox-
icillin and prednisolone and albuterol MDI.
The patient returned to the emergency department
two days later with similar symptoms and vomiting. He
had been receiving albuterol MDI every six hours for the
previous two days. His parents reported that he vomit-
ed shortly after receiving albuterol.
Previously, he had one episode of pneumonia that
improved with oral antibiotics.
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